понедельник, 17 сентября 2007 г.

Conference of germ resistance to begin in Chicago

CHICAGO (AFP) - Thousands of physicians and scientists meet here Monday to tackle the growing resistance of germs to antibiotics and the effects of global warming on them, at the world's biggest conference on disease-causing microbes.
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For the first time at the annual event, "the keynote session is going to be on climate change and the impact on human disease," Jim Sliwa, spokesman for the American Society for Microbiology which is organizing the event, told AFP.

"We know that climate change is going to change the pattern of infectious diseases," he said. "There are so many variables that we don't know what's going to happen."

"As global average temperature increases, we know ... for example, the malaria line in mountainous regions will continue to rise. This is fairly certain because above a certain altitude mosquitoes can't live," he said.

"We know also in the tropics influenza is year-round. There is no influenza season, so as the temperature rises the tropical areas expand and we'll get more year-round influenza."

Presentations at the conference, which is expected to bring together more than 12,000 physicians, researchers and other healthcare professionals from around the globe, will address the problem of drug-resistant microbes such as tuberculosis, which kills two million people each year.

Pharmaceutical labs will present research on growing challenges such as the resistance of certain staphylococcus bacteria, known as SARM, to antibiotics -- a source of many in-hospital infections, the association said.

They will also discuss the risks of a possible epidemic of a form of bird flu that is dangerous to humans and that could be passed from person to person.

Also on the agenda will be the results of clinical trials on the effectiveness of anti-retroviral therapies on cancers in people carrying HIV, the virus that causes AIDS.

British researchers are to make a presentation on the antibiotic effects of statin drugs, which reduce cholesterol. Research seems to have revealed the mechanism by which chemical action of the liver gives the anti-cholesterol drugs anti-microbe properties.

The association also plans to publish results of a survey on preventive hygiene, which looks at hand-washing habits among Americans. It examined the number of people who wash their hands after using public restrooms.

Other studies have shown that a worldwide campaign launched in 2005 by the World Health Organization to prompt medical personnel to wash and disinfect themselves before touching a patient yielded encouraging results, according to the conference program.

Inadequate hand-washing among doctors and nurses is responsible for millions of infections in hospitals around the world.

Researchers from France, Japan, and Britain will be in Chicago for the event, titled the Interscience Conference on Antimicrobial Agents and Chemotherapy. It runs to Thursday.

Doctors Scott Hammer and Lindsay Grayson, who head the conference's program committee expressed the confidence it will be "another successful educational event and an opportunity to exchange the latest information with scientists from around the world."



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China miners, power cos to invest in coal exchange

TAIYUAN, China, Sept 17 (Reuters) - Chinese power companies and the country's top coal miners, such as Shenhua Energy , will invest 1 billion yuan ($133 million) to set up a national exchange for the hydrocarbon in Shanxi province, China's top producer of the commodity.

An official from the state-owned Shanxi Coal Transportation & Sales Group told reporters investors for the first phase of the exchange also included China Coal Energy Co .

He gave no further details.

In August, Beijing gave the green light for the establishment of the China Taiyuan Coal Trading Market, a national exchange for coal trade, as it takes steps to free up coal prices after decades of state control.

The deputy governor of Shanxi province said on Sunday the exchange was likely to be launched before the end of the year.

It follows Beijing's decision last year to allow coal producers and consumers to negotiate prices and volumes among themselves for the 2007 annual supplies, a break from years of a heavy government hand in pricing.


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Endeca Advances State-of-the-Art in eCommerce and Online Media Through Debut of the Endeca Discovery Suite

CAMBRIDGE, Mass., & Shop.org, LAS VEGAS, Nev.--(BUSINESS WIRE)--Endeca Technologies, Inc., an enterprise information access software company, today unveiled the Endeca Discovery Suite, a new series of modules that will extend the capabilities of the Endeca Information Access Platform (IAP) and accelerate the development of next-generation eCommerce storefronts and media websites.

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Built to increase online revenue by boosting conversion rates and content consumption, the new capabilities will make it possible to rapidly design dynamic websites, accelerate online community building, and integrate online and offline assets. With the Discovery Suite, Endeca will rapidly bring to market new modular capabilities through collaborative research and development.

The suite's first two entries are the Social Navigation Module and Search Engine Marketing Module. Future modules will focus on personalization and recommendations, closed-loop reporting, multi-channel operations, and back-end integrations -- all with integral support for Web 2.0 interactivity.

"In 2001, Endeca pioneered the integration of search, Guided Navigation®, dynamic merchandising, and Content Spotlighting(TM) capabilities, redefining the search landscape and resetting expectations about the connection between findability and revenue. Search was no longer just a box and a long list of results, but a multi-faceted approach to driving virtually all aspects of the user experience," said Steve Papa, CEO of Endeca. "Developed through collaboration with our customers and our strategic partners, the Endeca Discovery Suite will once again raise the bar -- and expectations -- delivering first-of-their-kind capabilities for the next generation of websites and storefronts. The results will introduce entirely new kinds of revenue streams through the online channel and accelerate both front- and back-end innovation."

Social Navigation module: Boosts conversions and content consumption

Social navigation gives site owners new ways to take advantage of user-generated content they already have. It leverages this increasingly popular content -- product reviews, opinions, ratings, posts, user-generated tags -- as well as contributor profiles to help people discover information and products based on the paths and contributions of individuals with similar needs and preferences.

Endeca's Social Navigation Module can be used with best-of-breed social-media software from Endeca's strategic partners as well as in-house solutions, and includes:

  • Content adapters that provide out-of-the-box integration between the Endeca Information Access Platform and best-in-class user-review software from Bazaarvoice and PowerReviews
  • Dedicated content-acquisition and indexing capabilities to ingest all types of user-generated content, regardless of source or format
  • Tag-extraction capabilities to pull together and reveal common themes, concepts, and entities from text-based reviews, blogs, and posts for use in site navigation, search relevancy, and search-engine optimization
  • Tag-based visualization and navigation to complement static and dynamic site navigation, giving users more ways to explore and find desirable content and products
  • Meta-relational capabilities to link different content types by common concepts, allowing people to dynamically summarize the user generated content associated to any set of products
  • Content-aggregation abilities, combined with Endeca's patented search and Guided Navigation experience, enable the exploration of all reviews and other user-generated content spread across a site or collection of sites by the criteria most relevant to their goal
  • Profile-based navigation to help users find information and products by others with similar tastes, desires, and characteristics
  • Reference applications to speed development time and ensure best-practices for common use cases
  • "On-the-fly" graphical analytics components to improve customer insight and decision making by visually summarizing user-generated opinions into navigable charts and graphs

For more on social navigation applications in eCommerce and online media, see: http://endeca.com/discoverysuite.

Search Engine Marketing Module: Drives and converts site traffic

Endeca's Search Engine Marketing Module improves both organic and paid search strategies, driving qualified traffic and boosting content consumption, click-through rates and conversion rates. It does this by helping popular Internet search engines such as Google, Yahoo!, Microsoft Live Search, and Ask.com more accurately rank Endeca-powered sites. The module includes multiple, complementary SEO capabilities that make dynamic pages appear as static pages when being crawled or indexed by major Internet search engines, increasing both the number of pages indexed and their overall relevancy ranking. Endeca-powered businesses can automate the creation of literally billions of search-friendly landing pages that lead to increased page views, better customer acquisition, and increased revenue.

The Search Engine Marketing Module's capabilities include:

  • Next generation of the popular Endeca Sitemap Generator to simplify the task of indexing dynamic web pages by Google, Yahoo!, Microsoft Live Search, Ask.com, and other key Web search engines. It supports several out-of-the-box output formats, including HTML for websites and XML for Google Sitemaps, and is easily configured for other data feeds
  • Automated URL optimization API that turns dynamic page URLs into SEO-friendly text-based URLs. These give the appearance of static, keyword-rich directory pages, resulting in higher rankings for billions of dynamic pages

About Endeca

Endeca is a next-generation information access company, uniting the ease of search with the analytical power of business intelligence. Combining patented intellectual property, breakthrough science and a deep focus on user experience, the Endeca Information Access Platform helps people find, analyze and understand information in ways never before possible. Leading global organizations like ABN AMRO, Bank of America, Boeing, Cox Newspapers, Dice, The (US) Defense Intelligence Agency, The Home Depot, Hyatt, IBM, John Deere, The Library of Congress, Nike, and Walmart.com rely on Endeca to power business-critical applications that increase revenue, reduce costs and streamline operations.





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Public communication - Health Canada Endorsed Important Safety Information on KETEK(R) (telithromycin)

UPDATED INFORMATION on the antibiotic KETEK(R) (telithromycin)

LAVAL, QC, Sept. 5 /CNW Telbec/ - Sanofi-aventis Canada Inc., in consultation with Health Canada, would like to inform Canadian consumers of important new changes regarding the antibiotic KETEK(R) (telithromycin).
     -------------------------------------------------------------------------
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Do not take the antibiotic KETEK(R) to treat bronchitis, sinusitis,
tonsillitis or pharyngitis (sore throat).
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Upon review of the available safety information, including reported cases of severe liver problems, Health Canada has determined that the antibiotic KETEK(R) should no longer be prescribed or used to treat bronchitis, sinusitis, tonsillitis/pharyngitis (sore throat). If you are prescribed KETEK(R) for any of these conditions, ask your doctor about using other antibiotics instead.

KETEK(R) can still be used to treat community-acquired pneumonia ("CAP"). Before taking KETEK(R), discuss the possible side effects with your doctor, such as liver injury, fainting and difficulty seeing properly.

You should not take KETEK(R) if you have myasthenia gravis (a disease involving muscle weakness) or if you have had jaundice, hepatitis, or other signs of liver injury while or after taking KETEK(R) or macrolide antibiotics (such as clarithromycin (Biaxin(R)), azithromycin (Zithromax(TM)) or erythromycin).

Complete product information will be available in the official Canadian Product Monograph for KETEK(R) (see Part III: CONSUMER INFORMATION). The revised Product Monograph will be posted at www.sanofi-aventis.ca as soon as it is available.

Managing marketed health product-related adverse reactions depends on health care professionals and consumers reporting them. Reporting rates determined on the basis of spontaneously reported post-marketing adverse reactions are generally presumed to underestimate the risks associated with health product treatments. Any case of serious liver-related problems, exacerbations of myasthenia gravis, visual disturbances, fainting or other serious or unexpected adverse reactions in patients receiving KETEK(R) should be reported to sanofi-aventis Canada Inc. or Health Canada at the following addresses:

     -------------------------------------------------------------------------
Any suspected adverse reaction can be reported to:
sanofi-aventis Canada Inc.:
Toll-free telephone: 1-800-265-7927
Internet: www.sanofi-aventis.ca

Regular mail:
sanofi-aventis Canada Inc.
2150 St. Elzear Blvd. West
Laval, Quebec
H7L 4A8

Any suspected adverse reaction can also be reported to:
Canadian Adverse Drug Reaction Monitoring Program (CADRMP)
Marketed Health Products Directorate
HEALTH CANADA
Address Locator: 0701C
OTTAWA, Ontario, K1A 0K9
Tel: (613) 957-0337 or Fax: (613) 957-0335
To report an Adverse Reaction, consumers and health professionals may
call toll free:
Tel: 866 234-2345
Fax: 866 678-6789
cadrmp(at)hc-sc.gc.ca

The AR Reporting Form and the AR Guidelines can be found on the Health
Canada web site or in The Canadian Compendium of Pharmaceuticals and
Specialties.

http://www.hc-sc.gc.ca/dhp-mps/medeff/report-declaration/form/ar-
ei_form_e.html
http://www.hc-sc.gc.ca/dhp-mps/medeff/report-declaration/guide/ar-
ei_guide-ldir_e.html
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Sincerely,

original signed by

Franca Mancino, M. Sc.
Senior Director, Regulatory Affairs & Pharmacovigilance



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sanofi-aventis Canada Inc.

For further information

Health Canada: Marketed Health Products Directorate (MHPD), MHPD_DPSC@hc-sc.gc.ca, (613) 954-6522, Fax: (613) 952-7738

Resverlogix's HDL Preclinical Data is Published in Current Opinion in Investigational Drugs

CALGARY, ALBERTA--(MARKET WIRE)--Sep 12, 2007 -- Resverlogix Corp. ("Resverlogix") (Toronto:RVX.TO - News) is pleased to announce today that a portion of the Company's key preclinical data has been published in Current Opinion in Investigational Drugs. The article titled "Novel therapies to increase apolipoprotein AI and HDL for the treatment of atherosclerosis" is an article that details the many approaches to increasing ApoA-l/HDL.

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Mr. Donald McCaffrey, President & CEO of Resverlogix stated, "We are pleased to have our data included in this important peer reviewed journal. The data contained in this publication is an exciting segment of the comprehensive data set that Resverlogix will submit to the US Food and Drug Agency (FDA) as part of the Company's Investigational New Drug (IND) application. A Phase I Clinical trial is expected to start as early as the fourth quarter of 2007."

About ApoA-l/HDL

ApoA-I is the key protein in high-density lipoprotein (HDL or the "good cholesterol"). Over the past 50 years clinical studies have clearly demonstrated the beneficial role of ApoA-I by showing both the reversal of arterial plaque and reduction of CVD risk. Thereby ApoA-I has secured the moniker, the cardioprotective protein.

About Resverlogix Corp.

Resverlogix Corp. is a leading biotechnology company engaged in the development of novel therapies for important global medical markets with significant unmet needs. The NexVas(TM) program is the Company's primary focus which is to develop novel small molecules that enhance ApoA-l. These vital therapies address the grievous burden of atherosclerosis and other important diseases such as acute coronary syndrome, diabetes, Alzheimer's and other vascular disorders. The Company's secondary focus is TGF-Beta Shield(TM), a program that aims to address burgeoning grievous diseases, such as cancer and fibrosis. Resverlogix Corp. trades on the Toronto Stock Exchange (Toronto:RVX.TO - News). For further information please visit www.resverlogix.com.

This news release may contain certain forward-looking statements that reflect the current views and/or expectations of Resverlogix Corp. with respect to its performance, business and future events. Such statements are subject to a number of risks, uncertainties and assumptions. Actual results and events may vary significantly.


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Harvard Researchers Select S.C. BlueCross for National Honor

COLUMBIA, S.C., Sept. 10 /PRNewswire/ -- Harvard Medical School researchers have honored BlueCross BlueShield of South Carolina for an innovation that allows health care providers to obtain member pre- certifications in seconds over the Internet, making the pre-certification process more efficient and less costly.

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Researchers from the medical school's Department of Health Care Policy selected BlueCross' "Web Precert" tool as one of seven national BlueWorks® winners in honor of "BlueWorks for Providers Week," Sept. 10-14.

BlueWorks is a partnership between the Blue Cross and Blue Shield Association and Harvard's Department of Health Care Policy that recognizes innovative Blue Cross and Blue Shield companies working with doctors and hospitals to increase the efficiency and consistency of care delivery nationwide. Harvard researchers judged Blue Cross and Blue Shield local programs on innovation, efficacy, robust design and the potential for program replication. Since 2004, Harvard Medical School's Department of Health Care Policy has named 35 Blue Cross and Blue Shield programs as BlueWorks winners.

A pre-certification from the insurer to the provider is required for some medical services. With Web Precert, physicians go to the secure My Insurance Manager(SM) section of www.SouthCarolinaBlues.com or www.BlueChoiceSC.com and enter the member's identifying information to determine if pre-certification is required. If pre-certification is needed, the physician or staff member can enter clinical information online and receive a response for the majority of requests within seconds. About 13 percent of requests are held until additional clinical information is submitted.

Prior to implementation of Web Precert in 2005, doctors' offices submitted these requests by telephone or facsimile.

"I would say it saves me at least 15 to 20 minutes per pre-certification, and that is very important for me because I pre-cert for seven doctors," said Vicki Peebles, director of marketing and pre-certification for Blue Ridge Orthopaedics Associates in Seneca, S.C. "I can get backed up very quickly if I have to request a pre-certification by phone and I'm on hold for 30 minutes. I can complete a request online with BlueCross in less than five."

David Boucher, assistant vice president of Health Care Services for BlueCross, said Web Precert was developed because physicians requested the ability to obtain pre-authorizations online.

"BlueCross BlueShield of South Carolina is committed to providing our physicians, facilities and other health care providers with the information and tools they need to interact with us in the most efficient manner possible," Boucher said. "We believe the ability to access key authorization information quickly and easily promotes quality service and enables better health care for our members."

Dr. Barbara J. McNeil, head of Harvard's Department of Health Care Policy, said Web Precert allows physicians to communicate with BlueCross more efficiently.

"Contemporary managed care requires frequent communication between the provider and health plan," McNeil said. "This online tool allows providers to meet the reporting needs of the health plan with less effort, when and where it is most convenient for the provider."

Headquartered in Columbia, S.C., BlueCross BlueShield of South Carolina and wholly owned subsidiary BlueChoice HealthPlan of South Carolina Inc. are independent licensees of the Blue Cross and Blue Shield Association. BlueCross BlueShield of South Carolina and its family of companies include more than 20 subsidiaries involved in health insurance services, U.S. DOD health plan and Medicare contracts, and other insurance and employee benefits services.

BlueWorks is a registered mark of the Blue Cross and Blue Shield Association. My Insurance Manager is a service mark of BlueCross BlueShield of South Carolina.


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Tirico Takes Over Patrick's Old Slot on ESPN Radio

NEW YORK (AP) -- Mike Tirico will take over part of Dan Patrick's old sports talk time slot on ESPN Radio.

"The Mike Tirico Show" will debut Thursday from 1-3 p.m. EDT. Tirico serves as the play-by-play commentator for "Monday Night Football" and the NBA finals on ESPN.

Tirico was one of the original hosts when ESPN Radio launched in 1992.

"I do participate in the sports conversation every day by covering the NFL and the NBA and all the college sports that I've covered and my years doing `SportsCenter' and golf as well," he said. "I really do have a broad experience and have met a lot of people."

Patrick announced in July that he was leaving ESPN after 18 years.

The network has yet to determine which commentators will join Tirico on the show.

ESPN is owned by Walt Disney Co. and Heart Corp.





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